Pharmacology – ANTIHISTAMINES (MADE EASY)

Topics covered include: basic pathophysiology of allergic reaction, histamine and it’s actions, H1 and H2 histamine receptors, mast cells, parietal cells, mechanism of action of H1 and H2 antagonists. Drugs mentioned include first generation antihistamines; Brompheniramine, Chlorpheniramine, Clemastine, Cyproheptadine, Diphenhydramine, Doxylamine, Hydroxyzine, Meclizine, Promethazine; second generation antihistamines; Cetirizine, Desloratadine, Fexofenadine, Levocetirizine, Loratadine, Azelastine, Olopatadine, Ketotifen; H2 blockers; Cimetidine, Famotidine, Nizatidine, Ranitidine.