Pharmacology – DRUGS FOR DIABETES (MADE EASY)

Topics covered include: basic pathophysiology of diabetes mellitus type 1 & type 2, hyperglycemia, hypoglycemia, insulin production, pancreatic beta & alpha cells, glycogen, glucagon, glucose function. Mechanism of action of antidiabetic drugs; rapid, short, intermediate, long -acting insulin analogs, synthetic amylin, incretin mimetics, DPP-4 inhibitors, sulfonylureas, glinides, biguanides, thiazolidinediones, sodium-glucose cotransporter-2 inhibitors, and alpha-glucosidase inhibitors. Drugs mentioned include insulins Lispro, Aspart, Glulisine, Regular, NPH (isophane), Detemir, Glargine, Degludec; Pramlintide; Exenatide, Liraglutide; Alogliptin, Linagliptin, Saxagliptin, Sitagliptin; Glimepiride, Glyburide, Glipizide; Nateglinide, Repaglinide; Metformin; Pioglitazone, Rosiglitazone; Canagliflozin, Dapagliflozin; Acarbose, Miglitol.