Penicillins Explained Clearly by

Dr. Roger Seheult of illustrates the key differences between the various types of penicillin antibiotic medications:

0:57 – Discovery and brief history of penicillin
1:44 – Penicillinase
2:00 – Semi-synthetic penicillins (methicillin, oxacillin, nafcillin)
3:21 – Need for gram negative antibiotic coverage (E-coli, pseudomonas, etc.)
4:26 – Aminopenicillins (ampicillin, amoxicillin)
4:49 – Extended spectrum penicillin (piperacillin, ticarcillin)
5:14 – Beta-lactamase
5:42 – Beta-lactamase inhibitors (ampicillin/sulbactam and amoxicillin/clavulanic acid
6:35 – Piperacillin/tazobactam
6:54 – Ticarcillin and clavulanate
8:18 – Staph aureus and mutations against penicillin (PCN)
8:42 – MRSA – methicillin-resistant staphylococcus aureus
9:14 – Clindamycin, trimethoprim and sulfamethoxazole, quinolones, vancomycin, daptomycin, and linezolid
10:13 – A note about cross-reactivity / low platelets
10:33 – MSSA and nafcillin

Speaker: Roger Seheult, MD
Clinical and Exam Preparation Instructor
Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.

MedCram: Medical topics explained clearly including: Asthma, COPD, Acute Renal Failure, Mechanical Ventilation, Oxygen Hemoglobin Dissociation Curve, Hypertension, Shock, Diabetic Ketoacidosis (DKA), Medical Acid Base, VQ Mismatch, Hyponatremia, Liver Function Tests, Pulmonary Function Tests (PFTs), Adrenal Gland, Pneumonia Treatment, any many others. New topics are often added weekly- please subscribe to help support MedCram and become notified when new videos have been uploaded.


Recommended Audience: Health care professionals and medical students: including physicians, nurse practitioners, physician assistants, nurses, respiratory therapists, EMT and paramedics, and many others. Review for USMLE, MCAT, PANCE, NCLEX, NAPLEX, NDBE, RN, RT, MD, DO, PA, NP school and board examinations.

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Produced by Kyle Allred PA-C

Please note: MedCram medical videos, medical lectures, medical illustrations, and medical animations are for medical educational and exam preparation purposes, and not intended to replace recommendations by your health care provider.

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