Inside the Cell Membrane

Explore the parts of the cell membrane with The Amoeba Sisters! Video discusses phospholipid bilayer, cholesterol, peripheral proteins, integral proteins, glycoproteins, and glycolipids – as well as why the surface area to volume ratio is so important in cells. Expand for table of contents.

1:25 Membrane controls what goes in and out of cell
1:40 Importance of surface area to volume ratio
3:31 Cell Theory
4:00 Fluid Mosaic Model
4:28 Phospholipid and phospholipid bilayer
5:58 Cholesterol
6:23 Proteins (peripheral and integral)
7:43 Glycoproteins and glycolipids (carbohydrates bound to proteins and lipids)

Additional Vocabulary:

Recommended reading to learn more about HIV virus and its binding to the CD4 glycoprotein on certain types of immune cells:

This video mentions that phospholipid “flip-flop” isn’t very common. But it does happen! Recommended reading to learn about what that is:

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The Amoeba Sisters videos demystify science with humor and relevance. The videos center on Pinky’s certification and experience in teaching science at the high school level. Pinky’s teacher certification is in grades 4-8 science and 8-12 composite science (encompassing biology, chemistry, and physics). Amoeba Sisters videos only cover concepts that Pinky is certified to teach, and they focus on her specialty: secondary life science. For more information about The Amoeba Sisters, visit:

We cover the basics in biology concepts at the secondary level. If you are looking to discover more about biology and go into depth beyond these basics, our recommended reference is the FREE, peer reviewed, open source OpenStax biology textbook:

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