Down syndrome (trisomy 21) – causes, symptoms, diagnosis, & pathology

What is Down syndrome (trisomy 21)? Down syndrome is a set of symptoms that arise from a genetic abnormality, in which an individual’s cells have an extra copy of chromosome 21. Subscribe – More videos – Support us on Patreon –

This video covers the three main mechanisms leading to trisomy 21—nondisjunction, Robertsonian translocation, and mocaicism, as well as the more common complications and physical characteristics.

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Robbins Basic Pathology (text)
First Aid (text)
Biology—the dynamic science (text)

Script/audio/visuals: Tanner Marshall, MS
Reviewer: Rishi Desai, MD, MPH

Blood squirt sound effect by Mike Koenig –

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