Penicillins Explained Clearly

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Dr. Roger Seheult illustrates the key differences between the various types of penicillin antibiotic medications:

  • 0:57 – Discovery and brief history of penicillin
  • 1:44 – Penicillinase
  • 2:00 – Semi-synthetic penicillins (methicillin, oxacillin, nafcillin)
  • 3:21 – Need for gram negative antibiotic coverage (E-coli, pseudomonas, etc.)
  • 4:26 – Aminopenicillins (ampicillin, amoxicillin)
  • 4:49 – Extended spectrum penicillin (piperacillin, ticarcillin)
  • 5:14 – Beta-lactamase
  • 5:42 – Beta-lactamase inhibitors (ampicillin/sulbactam and amoxicillin/clavulanic acid
  • 6:35 – Piperacillin/tazobactam
  • 6:54 – Ticarcillin and clavulanate
  • 8:18 – Staph aureus and mutations against penicillin (PCN)
  • 8:42 – MRSA – methicillin-resistant staphylococcus aureus
  • 9:14 – Clindamycin, trimethoprim and sulfamethoxazole, quinolones, vancomycin, daptomycin, and linezolid
  • 10:13 – A note about cross-reactivity / low platelets
  • 10:33 – MSSA and nafcillin

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