Down syndrome (trisomy 21) – symptoms & pathophysiology

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What is Down syndrome (trisomy 21)?
Down syndrome is a set of symptoms that arise from a genetic abnormality, in which an individual’s cells have an extra copy of chromosome 21. This video covers the three main mechanisms leading to trisomy 21—nondisjunction, Robertsonian translocation, and mocaicism, as well as the more common complications and physical characteristics.

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