Pharmacology – DRUGS FOR HYPERLIPIDEMIA (MADE EASY)

Topics covered include: basic pathophysiology of hyperlipidemia, lipids, cholesterol, triglycerides, phospholipids, bile acids, fatty acids, lipoproteins, apolipoproteins, chylomicrons, VLDL, LDL, HDL, lipoprotein lipase, atherosclerosis, vascular inflammation. Mechanism of action of antihyperlipidemic drugs and their side effects; HMG-CoA reductase inhibitors (statins), nicotinic acid, fibrates, bile acid sequestrants, cholesterol absorption inhibitor, pcsk9 inhibitors, omega 3 fatty acids. Drugs mentioned include; atorvastatin, fluvastatin, lovastatin, pravastatin, rosuvastatin, simvastatin, niacin, fenofibrate, gemfibrozil, colesevelam, colestipol, cholestyramine, ezetimibe, evolocumab, alirocumab, docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), icosapent ethyl, fish oil.

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